PUBLICATIONS

450. Kalkman, E. D.; Hartwig, J. F. Direct Observation of Diastereomeric α-C-Bound Enolates during Enantioselective α-Arylations: Synthesis, Characterization, and Reactivity of Arylpalladium Fluorooxindole Complexes. J. Am. Chem. Soc.  2021143,  11741-11750.



446. Ray, R.; Hartwig, J.F. Oxalohydrazide Ligands for Copper-​Catalyzed C−​O Coupling Reactions with High Turnover Numbers. Angew. Chem. Int. Ed.  202160,  8203-8211.



438. Wang, J.Y.; Choi, K.; Zuend, S.J.; Borate, K.; Hartwig, J.F. Cross-Coupling between Hydrazine and Aryl Halides with Hydroxide Base at Low Loadings of Palladium by Rate-Determining Deprotonation of Bound Hydrazine. Angew. Chem. Int. Ed.  202060,  399-408.



433. Hartwig, J.F.; Shaughnessy, K.H.; Shekhar, S.; Green, R.A. Palladium-Catalyzed Amination of Aryl Halides. Organic Reactions  2020100,  853-943.

404. Haydl, A.M., Hartwig, J.F. Palladium-Catalyzed Methylation of Aryl, Heteroaryl, and Vinyl Boronate Esters. Org. Lett.  201921,  1337-1341.



401. Jiang, Q., Peacock, D.M., Hartwig, J.F., Cundari, T.R. Carbon (sp3)-nitrogen bond-forming reductive elimination from phosphine-ligated alkylpalladium (II) amide complexes: A DFT study. Tetrahedron  201975,  137-143.



338. Brusoe, A.T.; Hartwig, J.F. Palladium-Catalyzed Arylation of Fluoroalkylamines. J. Am. Chem. Soc.  2015137,  8460–8468.



332. Green, R.A.; Hartwig, J.F. Nickel-Catalyzed Amination of Aryl Chlorides with Ammonia or Ammonium Salts. Angew. Chem. Int. Ed.  201554,  3768-3772.



322. Green, R.A.; Hartwig, J.F. Palladium-Catalyzed Amination of Aryl Chlorides and Bromides with Ammonium Salts. Org. Lett.  201416,  4388−4391.



310. Ge. S.; Green, R.A.; Hartwig, J.F. Controlling First-Row Catalysts: Amination of Aryl and Heteroaryl Chlorides and Bromides with Primary Aliphatic Amines Catalyzed by a BINAP-Ligated Single-Component Ni(0) Complex. J. Am. Chem. Soc.  2014136,  1617-1627.



292. Fier, P.S.; Luo, J.; Hartwig, J.F. Copper-Mediated Fluorination of Arylboronate Esters. Identification of a Copper(III) Fluoride Complex. J. Am. Chem. Soc.  2013135,  2552−2559.



285. Chen, C.; Weng, Z.; Hartwig, J.F. Synthesis of Copper(I) Thiolate Complexes in the Thioetherification of Aryl Halides. Organometallics  201231,  8031–8036.



254. Giri, R.: Hartwig, J.F. Cu(I) Amido Complexes in the Ullmann Reaction. Reactions of Cu(I)-Amido Complexes with Iodoarenes with and without Autocatalysis by CuI. J. Am. Chem. Soc.   2010132,  15860-15863.



250. Klinkenberg, J.L.; Hartwig, J.F. Slow Reductive Elimination from Arylpalladium Parent Amido Complexes. J. Am. Chem. Soc.   2010132,  11830-11833.



246. Fernandez-Rodriguez, M.A.; Hartwig, J.F. One-Pot Synthesis of Unsymmetrical Diaryl Thioethers by Palladium-Catalyzed Coupling of Two Aryl Bromides and a Thiol Surrogate. Chem. Eur. J.  201016,  2355-2359.



242. Tye, J.W.; Weng, Z.; Giri, R.; Hartwig J.F. Copper(I) Phenoxide Complexes in the Etherification of Aryl Halides. Angew. Chem. Int. Ed.   201049,  2185-2189.



230. Vo, G.D.; Hartwig, J.F. Palladium-Catalyzed Coupling of Ammonia with Aryl Chlorides, Bromides, Iodides, and Sulfonates: A General Method for the Preparation of Primary Arylamines. J. Am. Chem. Soc.  2009131,  11049-11061.



227. Alvaro, E.; Hartwig, J.F. Resting State and Elementary Steps of the Coupling of Aryl Halides with Thiols Catalyzed by Alkylbisphosphine Complexes of Palladium. J. Am. Chem. Soc.  2009131,  7858–7868.



224. Fernandez-Rodríguez, M.A.; Hartwig, J.F. A General, Efficient, and Functional-Group-Tolerant Catalyst System for the Palladium-Catalyzed Thioetherification of Aryl Bromides and Iodides. J. Org. Chem.  200974,  1663-1672.



222. Hartwig, J.F. Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides. Acc. Chem. Res.  200841,  1534-1544.



216. Ogata, T.; Hartwig, J.F. Palladium-Catalyzed Amination of Aryl and Heteroaryl Tosylates at Room Temperature. J. Am. Chem. Soc. (Communication)  2008130,  13848-13849.



213. Shen, Q. and J.F. Hartwig [(CyPF-tBu)PdCl2]: An Air-Stable, One-Component, Highly Efficient Catalyst for Amination of Heteroaryl and Aryl Halides.. Org. Lett.  200818,  4109-4112.



212. Tye, J.W., Weng, Z., Johns, A. M., Incarvito, C. D., and J. F. Hartwig Copper Complexes of Anionic Nitrogen Ligands in the Amidation and Imidation of Aryl Halides.. J. Am. Chem. Soc.  2008130,  9971-9983.



207. Shen, Q., Ogata, T., and J.F. Hartwig Highly Reactive, General and Long-Lived Catalysts for Palladium-Catalyzed Amination of Heteroaryl and Aryl Chlorides, Bromides and Iodides: Scope and Structure-Activity Relationships.. J. Am. Chem. Soc.  2008130,  6586-6596.



205. Hagedorn, K.V., Varnavski, O., Hartwig, J.F; Goodson III, T. Exciton Trapping in an Organic Dendrimer Possessing No Energy Gradient.. J. Phys. Chem. C.  2008112,  2235-2238.



199. Stambuli, J.P., Weng, Z., Incarvito, C.D., and J. F. Hartwig Reductive Elimination of Ether from T-Shaped, Monomeric Arylpalladium Alkoxides.. Angew. Chem. Int. Ed.  200746,  7674-7677.



195. Shen, Q. and J. F. Hartwig Lewis Acid Acceleration of C-N Bond-Forming Reductive Elimination from Heteroarylpalladium Complexes and Catalytic Amidation of Heteroaryl Bromides. J. Am. Chem. Soc.  2007129,  7734-7735.



187. Shekhar, S., and J. F. Hartwig Effects of Bases and Halides on the Amination of Chloroarenes Catalyzed by Pd[P(tBu3)]2. Organometallics  200726,  340-351.



184. Johns, A. M, Tye, J. W., and J. F. Hartwig Relative Rates for the Aminations of h3-Allyl and h3-Benzyl Complexes of Palladium. J. Am. Chem. Soc.  2006128,  16010-16011.



182. Fernandez-Rodríguez, M. A., Shen, Q., and J. F. Hartwig Highly Efficient and Functional-Group-Tolerant Catalysts for the Palladium-Catalyzed Coupling of Aryl Chlorides with Thiols. Chem. Eur. J.  200612,  7782-7796.



177. Shen, Q., and J. F. Hartwig Palladium-Catalyzed Coupling of Ammonia and Lithium Amide with Aryl Halides. J. Am. Chem. Soc.  2006128,  10028-10029.



175. Fujita, K.I., Yamashita, M, Puschmann, F., Alvarez-Falcon, M.M., Incarvito, C.D., and J. F. Hartwig Organometallic Chemistry from Amidate Complexes. Reductive elimination of N-Aryl Amidates from Palladium(II). J. Am. Chem. Soc.  2006128,  9044-9045.



168. Fernández-Rodríguez, M. A., Shen, Q., and J. F. Hartwig A General and Long-Lived Catalyst for the Palladium-Catalyzed Coupling of Aryl Halides with Thiols. J. Am. Chem. Soc.  2006128,  2180-2181.



167. Shekhar, S., Ryberg, P., and J. F. Hartwig Oxidative Addition of Phenyl Bromide to Pd(BINAP) vs Pd(BINAP)(amine). Evidence for Addition to Pd(BINAP). Org. Lett.  20068,  851-854.



166. Shekhar, S., Ryberg, P., Hartwig, J. F., Mathew, J. S., Blackmond, D. G., Strieter, E. R., and S. L. Buchwald Reevaluation of the Mechanism of the Amination of Aryl Halides Catalyzed by BINAP-Ligated Palladium Complexes. J. Am. Chem. Soc.  2006128,  3584-3591.



164. Barrios-Landeros, F. and J. F. Hartwig Distinct Mechanisms for the Oxidative Addition of Chloro-, Bromo-, and Iodoarenes to a Bisphosphine Palladium(0) Complex with Hindered Ligands. J. Am. Chem. Soc.  2005127,  6944-6945.



163. Bae, C., Hartwig, J. F., Boaen Harris, N. K., Long, R. O., Anderson, K. S., and M. A. Hillmyer Catalytic Hydroxylation of Polypropylenes. J. Am. Chem. Soc.  2005127,  767-776.



158. Lee, D.-Y. and J. F. Hartwig Zinc Trimethylsilylamide as a Mild Ammonia Equivalent and Base for the Amination of Aryl Halides and Triflates. Org. Lett.  20057,  1169-1172.



154. Shen, Q., Shekhar, S., Stambuli, J. P., and J. F. Hartwig Highly Reactive, General, and Long-Lived Catalysts for Coupling Heteroaryl and Aryl Chlorides with Primary Nitrogen Nucleophiles.. Angew. Chem. Int. Ed.  200544,  1371-1375.

150. Yan, X. Z., Pawlas, J., Goodson, T., III and J. F. Hartwig Polaron Delocalization in Ladder Macromolecular Systems. J. Am. Chem. Soc.  2005127,  9105-9116.



149. Zhao, J., Goldman, A. S., and J. F. Hartwig Oxidative Addition of Ammonia to Form a Stable Monomeric Amido Hydride Complex. Science  2005307,  1080-1082.

142. Krug, C. and J. F. Hartwig Reactions of an Arylrhodium Complex with Aldehydes, Imines, Ketones, and Alkynones. New Classes of Insertion Reactions. Organometallics  200423,  4594-4607.



135. Shekhar, S. and J. F. Hartwig Distinct Electronic Effects on Reductive Eliminations of Symmetrical and Unsymmetrical Bis-Aryl Platinum Complexes.. J. Am. Chem. Soc.  2004126,  13016-13027.



125. Hooper, M. W., Utsunomiya, M., and J. F. Hartwig Scope and mechanism of palladium-catalyzed amination of five-membered heterocyclic halides. J. Org. Chem.  200368,  2861-2873.



124. Hooper, M. W. and J. F. Hartwig Understanding the Coupling of Heteroaromatic Substrates: Synthesis, Structures, and Reductive Eliminations of Heteroarylpalladium Amido Complexes. Organometallics  200322,  3394-3403.



117. Mann, G., Shelby, Q., Roy, A. H., and J. F. Hartwig Electronic and Steric Effects on the Reductive Elimination of Diaryl Ethers from Palladium(II). Organometallics  200322,  2775-2789.



116. Roy, A. H. and J. F. Hartwig Directly Observed Reductive Elimination of Aryl Halides from Monomeric Arylpalladium(II) Halide Complexes. J. Am. Chem. Soc.  2003125,  13944-13945.



113. Stauffer, S. R. and J. F. Hartwig Fluorescence Resonance Energy Transfer (FRET) as a High-Throughput Assay for Coupling Reactions. Arylation of Amines as a Case Study.. J. Am. Chem. Soc.  2003125,  6977-6985.



108. Yamashita, M., Cuevas Vicario, J. V., and J. F. Hartwig Trans Influence on the Rate of Reductive Elimination. Reductive Elimination of Amines from Isomeric Arylpalladium Amides with Unsymmetrical Coordination Spheres. J. Am. Chem. Soc.  2003125,  16347-16360.



104. Alcazar-Roman, L. M. and J. F. Hartwig Mechanistic studies on oxidative addition of aryl halides and triflates to Pd(BINAP)2 and structural characterization of the product from aryl triflate addition in the presence of amine. Organometallics  200221,  491-502.



94. Kuwano, R., Utsunomiya, M., and J. F. Hartwig Aqueous hydroxide as a base for palladium-catalyzed amination of aryl chlorides and bromides. J. Org. Chem.  200267,  6479-6486.



90. Ranasinghe, M. I., Varnavski, O. P., Pawlas, J., Hauck, S. I., Louie, J., Hartwig, J. F., and T. Goodson III Femtosecond excitation energy transport in triarylamine dendrimers. J. Am. Chem. Soc.  2002124,  6520-6521.



87. Stambuli, J. P., Buhl, M., and J. F. Hartwig Synthesis, characterization, and reactivity of monomeric, arylpalladium halide complexes with a hindered phosphine as the only dative ligand. J. Am. Chem. Soc.  2002124,  9346-9347.



84. Alcazar-Roman, L. M. and J. F. Hartwig Mechanism of aryl chloride amination: Base-induced oxidative addition. J. Am. Chem. Soc.  2001123,  12905-12906.

83. Chae, H. K., Eddaoudi, M., Kim, J., Hauck, S. I., Hartwig, J. F., O'Keeffe, M., and O. M. Yaghi Tertiary building units: Synthesis, structure, and porosity of a metal-organic dendrimer framework (MODF-1). J. Am. Chem. Soc.  2001123,  11482-11483.

77. Lee, S., M. Jorgensen, and J. F. Hartwig Palladium-catalyzed synthesis of arylamines from aryl halides and lithium bis(trimethylsilyl)amide as an ammonia equivalent. Org. Lett.  20013,  2729-2732.



74. Roy, A. H. and J. F. Hartwig Reductive elimination of aryl halides from palladium(II). J. Am. Chem. Soc.  2001123,  1232-1233.

70. Shelby, Q.; Kataoka, N.; Mann, G.; Hartwig, J.F. Unusual in situ Ligand Modification to Generate a Catalyst for Room Temperature Aromatic C-O Bond Formation. J. Am. Chem. Soc.  2000122,  10718-10719.

69. Alcazar-Roman, L. M., Hartwig, J. F., Rheingold, A. L., Liable-Sands, L. M., and I. A. Guzei Mechanistic studies of the palladium-catalyzed amination of aryl halides and the oxidative addition of aryl bromides to Pd(BINAP)2 and Pd(DPPF)2: An unusual case of zero-order kinetic behavior and product inhibition. J. Am. Chem. Soc.  2000122,  4618-4630.

63. Stauffer, S. R., Lee, S., Stambuli, J. P., Hauck, S. I., and J. F. Hartwig High turnover number and rapid, room-temperature amination of chloroarenes using saturated carbene ligands. Org. Lett.  20002,  1423-1426.



60. Goodson, F. E., Hauck, S. I., and J. F. Hartwig Palladium-catalyzed synthesis of pure, regiodefined polymeric triarylamines. J. Am. Chem. Soc.  1999121,  7527-7539.

58. Hartwig, J. F., Kawatsura, M., Hauck, S. I., Shaughnessy, K. H., and L. M. Alcazar-Roman Room-temperature palladium-catalyzed amination of aryl bromides and chlorides and extended scope of aromatic C-N bond formation with a commercial ligand. J. Org. Chem.  199964,  5575-5580.



57. Hauck, S. I., Lakshmi, K. V. and J. F. Hartwig Tetraazacyclophanes by palladium-catalyzed aromatic amination. Geometrically defined, stable, high-spin diradicals. Org. Lett.  19991,  2057-2060.



55. Mann, G., Incarvito, C. D., Rheingold, A. L., and J. F. Hartwig Palladium-catalyzed C-O coupling involving unactivated aryl halides. Sterically induced reductive elimination to form the C-O bond in diaryl ethers. J. Am. Chem. Soc.  1999121,  3224-3225.

50. Goodson, F. E. and J. F. Hartwig Regiodefined poly(N-arylaniline)s and donor-acceptor copolymers via palladium-mediated amination chemistry. Macromolecules  199831,  1700-1703.

49. Hamann, B. C. and J. F. Hartwig Sterically hindered chelating alkyl phosphines provide large rate accelerations in palladium-catalyzed amination of aryl iodides, bromides, and chlorides, and the first amination of aryl tosylates. J. Am. Chem. Soc.  1998120,  12706-12706.

47. Hamann, B. C. and J. F. Hartwig Systematic variation of bidentate ligands used in aryl halide amination. Unexpected effects of steric, electronic, and geometric perturbations. J. Am. Chem. Soc.  1998120,  3694-3703.

46. Hartwig, J. F. Carbon-heteroatom bond-forming reductive eliminations of amines, ethers, and sulfides. Acc. Chem. Res.  199831,  852-860.

45. Hartwig, J. F. Transition metal catalyzed synthesis of arylamines and aryl ethers from aryl halides and triflates: Scope and mechanism. Angew. Chem. Int. Ed.  199837,  2047-2067.

44. Hartwig, J. F. Synthesis, structure, and reactivity of a palladium hydrazonato complex: A new type of reductive elimination reaction to form C-N bonds and catalytic arylation of benzophenone hydrazone. Angew. Chem. Int. Ed.  199837,  2090-2093.

43. Louie, J. and J. F. Hartwig The largest discrete oligo(m-aniline). An exponential growth strategy using palladium-catalyzed amination of aryl sulfonates. Macromolecules  199831,  6737-6739.

42. Mann, G., Baranano, D., Hartwig, J. F., Rheingold, A. L., and I. A. Guzei Carbon-sulfur bond-forming reductive elimination involving sp-, sp2-, and sp3-hybridized carbon. Mechanism, steric effects, and electronic effects on sulfide formation. J. Am. Chem. Soc.  1998120,  9205-9219.

41. Mann, G., Hartwig, J. F., Driver, M. S., and C. Fernandez-Rivas Palladium-catalyzed C-N(sp2) bond formation: N-arylation of aromatic and unsaturated nitrogen and the reductive elimination chemistry of palladium azolyl and methyleneamido complexes. J. Am. Chem. Soc.  1998120,  827-828.

38. Baranano, D.; Mann, G., and Hartwig, J. F. Nickel and palladium-catalyzed cross-couplings that form carbon-heteroatom and carbon-element bonds. Current Organic Chemistry  19971,  287-305.

33. Louie, J., Hartwig, J. F., and A. J. Fry Discrete high molecular weight triarylamine dendrimers prepared by palladium-catalyzed amination. J. Am. Chem. Soc.  1997119,  11695-11696.

32. Louie, J., Driver, M. S., Hamann, B. C., and J. F. Hartwig Palladium-catalyzed amination of aryl triflates and importance of triflate addition rate. J. Org. Chem.  199762,  1268-1273.



31. Mann, G. and J. F. Hartwig Palladium-catalyzed formation of diaryl ethers from aryl bromides. Electron poor phosphines enhance reaction yields. Tetrahedron Letters  199738,  8005-8008.

30. Mann, G. and J. F. Hartwig Nickel- vs palladium-catalyzed synthesis of protected phenols from aryl halides. J. Org. Chem.  199762,  5413-5418.



27. Driver, M. S. and J. F. Hartwig A second-generation catalyst for aryl halide amination: Mixed secondary amines from aryl halides and primary amines catalyzed by (DPPF)PdCl2. J. Am. Chem. Soc.  1996118,  7217-7218.

22. Hartwig, J. F., Richards, S., Baranano, D., and F. Paul Influences on the relative rates for C-N bond-forming reductive elimination and beta-hydrogen elimination of amides. A case study on the origins of competing reduction in the palladium-catalyzed amination of aryl halides. J. Am. Chem. Soc.  1996118,  3626-3633.

17. Louie, J., F. Paul, and J. F. Hartwig Catalysis with platinum-group alkylamido complexes, the active palladium amide in catalytic aryl halide aminations as deduced from kinetic data and independent generation. Organometallics  199615,  2794-2805.



16. Mann, G. and J. F. Hartwig Palladium alkoxides: Potential intermediacy in catalytic amination, reductive elimination of ethers, and catalytic etheration. Comments on alcohol elimination from Ir(III). J. Am. Chem. Soc.  1996118,  13109-13110.

14. Baranano, D. and J. F. Hartwig Carbon-Heteroatom Bond-Forming Reductive Elimination - Mechanism, Importance of Trapping Reagents, and Unusual Electronic Effects During Formation of Aryl Sulfides. J. Am. Chem. Soc.  1995117,  2937-2938.

13. Driver, M. S. and J. F. Hartwig A Rare, Low-Valent Alkylamido Complex, a Diphenylamido Complex, and Their Reductive Elimination of Amines by 3-Coordinate Intermediates. J. Am. Chem. Soc.  1995117,  4708-4709.

12. Paul, F., Patt, J., and J. F. Hartwig Structural Characterization and Simple Synthesis of (Pd[P(O-Tol)3]2), Dimeric Palladium(II) Complexes Obtained by Oxidative Addition of Aryl Bromides, and Corresponding Monometallic Amine Complexes. Organometallics  199514,  3030-3039.

11. Hartwig, J. F. and F. Paul Oxidative Addition of Aryl Bromide after Dissociation of Phosphine from a 2-Coordinate Palladium(0) Complex, Bis(Tri-O-Tolylphosphine)Palladium(0). J. Am. Chem. Soc.  1995117,  5373-5374.

10. Louie, J. and J. F. Hartwig Transmetalation Involving Organotin Aryl, Thiolate, and Amide Compounds - an Unusual Type of Dissociative Ligand Substitution-Reaction. J. Am. Chem. Soc.  1995117,  11598-11599.

9. Louie, J. and J. F. Hartwig Palladium-Catalyzed Synthesis of Arylamines from Aryl Halides - Mechanistic Studies Lead to Coupling in the Absence of Tin Reagents. Tetrahedron Letters  199536,  3609-3612.

5. Paul, F., Patt, J., and J. F. Hartwig Palladium-Catalyzed Formation of Carbon-Nitrogen Bonds - Reaction Intermediates and Catalyst Improvements in the Hetero Cross-Coupling of Aryl Halides and Tin Amides. J. Am. Chem. Soc.  1994116,  5969-5970.