OUR CHEMISTRY

Our research group aims to discover, develop and understand new transition metal-catalyzed reactions. The discovery of fundamentally new transition metal chemistry and its development into practical, catalytic synthetic methods is a theme of our research.

NEWS & EVENTS



July 2021: Prof. Erik Romero will begin his new position as an Assistant Professor of Chemistry and Biochemistry at University of California, San Diego, CA.

May 2021: Prof. Yang Gu will begin his new position as an Associate Professor at Shenzhen Institute of Advanced Techonolgy, Chinese Academy of Sciences, P.R. China.

February 2021: The lab celebrates Black History Month by highlighting specific Black chemists and their accomplishments. Check out our presentations here.

January 2021: Dr. Pengfei Ji will begin his new position as a Professor in the Department of Chemistry at Zhejiang University, China.

January 2021: Dr. Zhennan Liu will begin her new position as a Research Scientist at the Institute of Chemical and Engineering Sciences, Singapore.

October 2020: Prof. John F. Hartwig won the 2021 Arthur C. Cope Award.

October 2020: Dr. Adrian Tlahuext Aca will begin his new position as a Senior Scientist at Corteva Agriscience in Indianapolis, IN.

October 2020: Dr. Jean-Denys Hamel will begin his new position as an Assistant Professor in the Department of Chemistry and Biochemistry at University of of Lethbridge, Canada.

September 2020: Dr. Liye Chen will begin his new position as a Postdoctoral Scholar in the Department of Cellular Molecular Pharmacology at University of California San Francisco, CA.

September 2020: Dr. Caleb Karmel will begin his new position as a Postdoctoral Scholar at Cardiovascular Research Inst., School of Medicine, University of California San Francisco.

RECENT PUBLICATIONS

Fuentes, M. A.; Gava, R.; Saper, N. I.; Romero, E.; Caballero, A.; Hartwig, J. F.; Pérez, P. J. Copper-Catalyzed Dehydrogenative Amidation of Light Alkanes. Angew. Chem. Int. Ed.   2021None,  None.
Chen, L.; Malollari, K.G.; Ullana, A.; Hartwig, J.F. Ruthenium-​Catalyzed, Chemoselective and Regioselective Oxidation of Polyisobutene. J. Am. Chem. Soc.  2021143,  4531-4535.
Fawcett, A.; Keller, M.J.; Herrera, Z.; Hartwig, J.F. Site selective chlorination of C(sp3)​-​H bonds suitable for late-​Stage functionalization. Angew. Chem. Int. Ed.  202160,  8276-8283.
Ray, R.; Hartwig, J.F. Oxalohydrazide Ligands for Copper-​Catalyzed C-​O Coupling Reactions with High Turnover Numbers. Angew. Chem. Int. Ed.  202160,  8203-8211.
Ji, P.; Park, J.; Gu, Y.; Clark, D.S.; Hartwig, J.F. Abiotic reduction of ketones with silanes catalysed by carbonic anhydrase through an enzymatic zinc hydride. Nat. Chem.  202113,  312-318.
Chen, L.; Malollari, K.G.; Uliana, A.; Sanchez, D.; Messersmith, P.B.; Hartwig, J.F. Selective, Catalytic Oxidations of C-H Bonds in Polyethylenes Produce Functional Materials with Enhanced Adhesion. Chem  20217,  137-145.
Tlahuext-Aca, A.; Lee, S. Y.; Sakamoto, S.; Hartwig, J.F. Direct Arylation of Simple Arenes with Aryl Bromides by Synergistic Silver and Palladium Catalysis. ACS Catal.  202111,  1430-1434.
Tlahuext-Aca, A.; Hartwig, J.F. Site-Selective Silver-Catalyzed C-H Bond Deuteration of Five-Membered Aromatic Heterocycles and Pharmaceuticals. ACS Catal.  202111,  1119-1127.
Ma, S.; Hill, C.K.; Olen, C.L.; Hartwig, J.F. Ruthenium-Catalyzed Hydroamination of Unactivated Terminal Alkenes with Stoichiometric Amounts of Alkene and an Ammonia Surrogate by Sequential Oxidation and Reduction. J. Am. Chem. Soc.  2021143,  359-368.
Xi, Y.; Ma, S.; Hartwig, J.F. Catalytic asymmetric addition of an amine N-H bond across internal alkenes. Nature  2020588,  254-260.