OUR CHEMISTRY

Our research group aims to discover, develop and understand new transition metal-catalyzed reactions. The discovery of fundamentally new transition metal chemistry and its development into practical, catalytic synthetic methods is a theme of our research.

NEWS & EVENTS



October 2020: Prof. John F. Hartwig won the 2021 Arthur C. Cope Award.

October 2020: Dr. Adrian Tlahuext Aca will begin his new position as a Senior Scientist at Corteva Agriscience in Indianapolis, IN.

October 2020: Dr. Jean-Denys Hamel will begin his new position as an Assistant Professor in the Department of Chemistry and Biochemistry at University of of Lethbridge, Canada.

September 2020: Dr. Liye Chen will begin his new position as a Postdoctoral Scholar in the Department of Cellular Molecular Pharmacology at University of California San Francisco, CA.

September 2020: Dr. Caleb Karmel will begin his new position as a Postdoctoral Scholar at Cardiovascular Research Inst., School of Medicine, University of California San Francisco.

May 2020: Dr. Justin Wang will begin his new position as a Senior Scientist at Chevron Corporation, Richmond, CA.

May 2020: Dr. Bo Su will begin his new position as a Professor in the Department of Chemistry at Nankai University, China.

March 2020: Dr. Sean Natoli will begin his new position as a Research Scientist at Procter and Gamble Company in Cincinnati, OH.

February 20, 2020: Cambridge Merck Lectureship at University of Cambridge, England.

February 18 - 19, 2020: British Scientific Society (SCI) Conference at University of Machester, England.

RECENT PUBLICATIONS

Hartwig, J.F.; Shaughnessy, K.H.; Shekhar, S.; Green, R.A. Palladium-Catalyzed Amination of Aryl Halides. Organic Reactions  2020100,  853-943.
Xi, Y.; Su, B.; Qi, X.; Pedram, S.; Liu, P.; Hartwig, J.F. Application of Trimethylgermanyl-Substituted Bisphosphine Ligands with Enhanced Dispersion Interactions to Copper-Catalyzed Hydroboration of Disubstituted Alkenes. J. Am. Chem. Soc.  2020142,  ASAP.
Richers, C.P.; Roediger, S.; Laserna, V.; Hartwig, J.F. Effects of Ligands on the Migratory Insertion of Alkenes into Rhodium–Oxygen Bonds. Chem. Sci.  202011,  10449-10456.
Butcher, T.W.; Yang, J.L.; Hartwig, J.F. Copper-Catalyzed Defluorinative Borylation and Silylation of gem-Difluoroallyl Groups. Org. Lett.  202022,  6805-6809.
Hanna, S.; Wills, T.; Butcher, T.W.; Hartwig, J.F. Palladium-Catalyzed Oxidative Dehydrosilylation for Contra-Thermodynamic Olefin Isomerization. ACS Catal.  202010,  8736-8741.
Butcher, T.W.; Yang, J.L.; Amberg, W.M.; Watkins, N.B.; Wilkinson, N.D.; Hartwig, J.F. Desymmetrization of difluoromethylene groups by C-F bond activation. Nature  2020583,  548-553.
Karmel, C.; Hartwig, J.F. Mechanism of the iridium-catalyzed silylation of aromatic C-H bonds. J. Am. Chem. Soc.  2020142,  10494-10505.
Buchwald, S.L.; Hartwig, J.F. In Praise of Basic Research as a Vehicle to Practical Applications: Palladium-Catalyzed Coupling to Form Carbon-Nitrogen Bonds. Isr. J. Chem.   202060,  177-179.
Su, B; Bunescu, A.; Qiu, Y.; Zuend, S.J.; Ernst, M.; Hartwig, J.F. Palladium-Catalyzed Oxidation of C(sp3)H Bonds of Primary Alkylamines through a Rare Four-Membered Palladacycle Intermediate. J. Am. Chem. Soc.  2020142,  7912-7919.
Saper, N.I.; Ohgi, A.; Small, D.W.; Semba, K.; Nakao, Y.; Hartwig, J.F. Nickel-catalyzed anti-Markovnikov hydroarylation of unactivated alkenes with unactivated arenes facilitated by non-covalent interactions. Nat. Chem.  202012,  276-283.