Nickel-Catalyzed Amination of Aryl Chlorides with Ammonia or Ammonium Salts

Nickel-Catalyzed Amination of Aryl Chlorides with Ammonia or Ammonium Salts

Angew. Chem. Int. Ed.  201554,  3768-3772.

The nickel-catalyzed amination of aryl chlorides to form primary arylamines occurs with ammonia or ammonium sulfate and a well-defined single-component nickel(0) precatalyst containing a Josiphos ligand and an η2-bound benzonitrile ligand. This system also catalyzes the coupling of aryl chlorides with gaseous amines in the form of their hydrochloride salts. Read more on publisher's site.