Palladium-Catalyzed γ-Arylation of α,β-Unsaturated Esters from Silyl Ketene Acetals

Smarty cat: A method for the palladium-catalyzed γ-arylation of α,β-unsaturated esters via silyl ketene acetals in the absence of fluoride has been developed. The coupling proceeds with electron-rich and electron-poor aryl bromides and vinyl bromides in high yields with a high tolerance for other functional groups.