Primary tert- and sec-Allylamines via Palladium-Catalyzed Hydroamination and Allylic Substitution with Hydrazine and Hydroxylamine Derivatives.

Primary tert- and  sec-Allylamines via Palladium-Catalyzed Hydroamination and Allylic  Substitution with Hydrazine and Hydroxylamine Derivatives.

Angew. Chem. Int. Ed.  200746,  7259-7261.

Amines of control: Palladium-catalyzed reactions of hydrazine and hydroxylamine derivatives with dienes and allylic esters form products from C[BOND]N bond formation at the more substituted position of the allyl intermediate with a broad range of ligands on palladium (see scheme; X=NCPh2 or OR; Ac=acetyl). These reactions provide a route to highly substituted primary amines by facile cleavage of the N[BOND]O and N[BOND]N bonds. Read more on publisher's site.