Carbon-Oxygen Bond Formation between a Terminal Alkoxo Ligand and a Coordinated Olefin. Evidence for Olefin Insertion into a Rhodium-Alkoxide

Carbon-Oxygen Bond Formation between a Terminal Alkoxo Ligand and a Coordinated Olefin. Evidence for Olefin Insertion into a Rhodium-Alkoxide

J. Am. Chem. Soc.  2006,  128,  9642-9643.

Preparation and reactivity of a series of bis(phosphine) rhodium(I) alkoxides stabilized by intramolecular olefin coordination are reported. {Rh(PEt3)2[κ1:η2-OCRR‘(CH2)nCHCH2]} (n = 1, 2) were prepared via alcoholysis of {Rh(PEt3)2[N(SiMe3)2]} by the corresponding alcohols HOCRR‘(CH2)nCHCH2. The in situ generated {Rh(PEt3)2[κ1:η2-OCRR‘(CH2)2CHCH2]} were not stable at ambient temperatures and decomposed in the presence of added PEt3 to afford 2,2-disubstituted-5-methylenetetrahydrofurans and [(PEt3)4Rh−H] in good to high yields. Kinetic and deuterium labeling results support a syn-oxyrhodation pathway via direct olefin insertion into a Rh−O bond, followed by rapid β-hydride elimination. In comparison, {Rh(PEt3)2[κ1:η2-OCRR‘CH2CHCH2]} are isolated as stable crystals, and the Rh−olefin interactions are evidenced by an X-ray structure. Heating of these complexes generated [Rh(PEt3)2(η2-allyl)] and the corresponding ketones in high yields following an apparent β-allyl elimination pathway. Read more on publisher's site.