OUR CHEMISTRY

Our research group aims to discover, develop and understand new transition metal-catalyzed reactions. The discovery of fundamentally new transition metal chemistry and its development into practical, catalytic synthetic methods is a theme of our research.

RECENT NEWS



March 2019: Dr. Xingyu Jiang will begin his new position as a Senior Scientist at Pharmacyclics, an AbbVie company.

December 2018: Dr. Mingshuo Zeng will begin her new position as a Senior Scientist in the Department of Discovery Chemistry at Genentech, South San Francisco, CA.

June 2018: Dr. Taegyo Lee will begin his new position as a Senior Scientist at Pfizer Inc., Groton, CT.

April 2018: Dr. Eunhye Kang will begin her new position as a Scientist at LG in South Korea.

April 2018: Dr. Haoquan Li will begin his new position as a Senior Scientist at Dow Chemical Company, Midland, MI.

April 2018: Dr. Ala Bunescu will begin her new position as a Postdoctoral Fellow at Dept. of Chemistry, University of Cambridge, United Kingdom.

April 2018: Dr. Masahiro Kojima will begin his new position as an Assistant Professor at Dept. of Chemistry, Hokkaido University, Sapporo, Japan.

April 2018: Dr. Qing-Wei Zhang will begin his new position as an Assistant Professor at Dept. of Chemistry, University of Science and Technology of China.

January 2018: Dr. Sarah Lee will begin her new position as an Assistant Professor at Dept. of Chemistry, Yonsei University, Seoul, South Korea.

January 2018: Dr. Rhett Baillie will begin his new position as a Scientist at Dow Chemical Company, Houston, TX.

RECENT PUBLICATIONS

He, Z.T., Jiang, X., Hartwig, J.F. Stereodivergent Construction of Tertiary Fluorides in Vicinal Stereogenic Pairs by Allylic Substitution with Iridium and Copper Catalysts. J. Am. Chem. Soc.  20190,  XXX-XXX.
He, Z.T., Hartwig, J.F. Palladium-Catalyzed α-Arylation of Carboxylic Acids and Secondary Amides via a Traceless Protecting Strategy. J. Am. Chem. Soc.  2019141,  11749-11753.
Hartwig, J.F., Romero, E.A. Iridium-catalyzed silylation of unactivated C-H bonds. Tetrahedron  201975,  4059-4070.
Karmel, C., Chen, Z., Hartwig, J.F. Iridium-Catalyzed Silylation of C–H Bonds in Unactivated Arenes: A Sterically Encumbered Phenanthroline Ligand Accelerates Catalysis. J. Am. Chem. Soc.  2019141,  7063-7072.
Hanna, S., Holder, J.C., Hartwig, J.F. A Multicatalytic Approach to the Hydroaminomethylation of α-Olefins. Angew. Chem. Int. Ed.  201958,  3368-3372.
Haydl, A.M., Hartwig, J.F. Palladium-Catalyzed Methylation of Aryl, Heteroaryl, and Vinyl Boronate Esters. Org. Lett.  201921,  1337-1341.
He, Z.T., Hartwig, J.F. Enantioselective α-functionaliations of ketones via allylic substitution of silyl enol ethers. Nat. Chem.  201911,  177.
Natoli, S.N., Hartwig, J.F. Noble-Metal Substitution in Hemoproteins: An Emerging Strategy for Abiological Catalysis. Acc. Chem. Res.  201952,  326-335.
Jiang, Q., Peacock, D.M., Hartwig, J.F., Cundari, T.R. Carbon (sp3)-nitrogen bond-forming reductive elimination from phosphine-ligated alkylpalladium (II) amide complexes: A DFT study. Tetrahedron  201975,  137-143.
He, Z., Li, H., Haydl, A. M., Whiteker, G. T., Hartwig, J. F. Trimethylphosphate as a Methylating Agent for Cross Coupling: A Slow-Release Mechanism for the Methylation of Arylboronic Esters. J. Am. Chem. Soc.  2018140,  17197-17202.