OUR CHEMISTRY

Our research group aims to discover, develop and understand new transition metal-catalyzed reactions. The discovery of fundamentally new transition metal chemistry and its development into practical, catalytic synthetic methods is a theme of our research.

RECENT NEWS



March 2019: Dr. Xingyu Jiang will begin his new position as a Senior Scientist at Pharmacyclics, an AbbVie company.

December 2018: Dr. Mingshuo Zeng will begin her new position as a Senior Scientist in the Department of Discovery Chemistry at Genentech, South San Francisco, CA.

June 2018: Dr. Taegyo Lee will begin his new position as a Senior Scientist at Pfizer Inc., Groton, CT.

April 2018: Dr. Eunhye Kang will begin her new position as a Scientist at LG in South Korea.

April 2018: Dr. Haoquan Li will begin his new position as a Senior Scientist at Dow Chemical Company, Midland, MI.

April 2018: Dr. Ala Bunescu will begin her new position as a Postdoctoral Fellow at Dept. of Chemistry, University of Cambridge, United Kingdom.

April 2018: Dr. Masahiro Kojima will begin his new position as an Assistant Professor at Dept. of Chemistry, Hokkaido University, Sapporo, Japan.

April 2018: Dr. Qing-Wei Zhang will begin his new position as an Assistant Professor at Dept. of Chemistry, University of Science and Technology of China.

January 2018: Dr. Sarah Lee will begin her new position as an Assistant Professor at Dept. of Chemistry, Yonsei University, Seoul, South Korea.

January 2018: Dr. Rhett Baillie will begin his new position as a Scientist at Dow Chemical Company, Houston, TX.

RECENT PUBLICATIONS

He, Z.T., Hartwig, J.F. Palladium-Catalyzed α-Arylation of Carboxylic Acids and Secondary Amides via a Traceless Protecting Strategy. J. Am. Chem. Soc.  20190,  XXX-XXX.
Hartwig, J.F., Romero, E.A. Iridium-catalyzed silylation of unactivated C-H bonds. Tetrahedron  201975,  4059-4070.
Karmel, C., Chen, Z., Hartwig, J.F. Iridium-Catalyzed Silylation of C–H Bonds in Unactivated Arenes: A Sterically Encumbered Phenanthroline Ligand Accelerates Catalysis. J. Am. Chem. Soc.  2019141,  7063-7072.
Hanna, S., Holder, J.C., Hartwig, J.F. A Multicatalytic Approach to the Hydroaminomethylation of α-Olefins. Angew. Chem. Int. Ed.  201958,  3368-3372.
Haydl, A.M., Hartwig, J.F. Palladium-Catalyzed Methylation of Aryl, Heteroaryl, and Vinyl Boronate Esters. Org. Lett.  201921,  1337-1341.
He, Z.T., Hartwig, J.F. Enantioselective α-functionaliations of ketones via allylic substitution of silyl enol ethers. Nat. Chem.  201911,  177.
Natoli, S.N., Hartwig, J.F. Noble-Metal Substitution in Hemoproteins: An Emerging Strategy for Abiological Catalysis. Acc. Chem. Res.  201952,  326-335.
Jiang, Q., Peacock, D.M., Hartwig, J.F., Cundari, T.R. Carbon (sp3)-nitrogen bond-forming reductive elimination from phosphine-ligated alkylpalladium (II) amide complexes: A DFT study. Tetrahedron  201975,  137-143.
He, Z., Li, H., Haydl, A. M., Whiteker, G. T., Hartwig, J. F. Trimethylphosphate as a Methylating Agent for Cross Coupling: A Slow-Release Mechanism for the Methylation of Arylboronic Esters. J. Am. Chem. Soc.  2018140,  17197-17202.
Su, B.; Lee, T.; Hartwig, J.F. Iridium-Catalyzed, β-Selective C(sp3)-H Silylation of Aliphatic Amines to Form Silapyrrolidines and 1,2-Amino Alcohols. J. Am. Chem. Soc.  2018140,  18032-18038.